What remains to be discovered

Sci Du Jour asks:

What technological/scientific advances/discoveries are you most looking forward to in the next 25 years?

A few years ago I read John Maddox’s What Remains to Be Discovered: Mapping the Secrets of the Universe, the Origins of Life, and the Future of the Human Race (Amazon link). It’s an amazingly broad survey of all the bleeding edges of science and tech today. I most remember the bits about materials tech—all sorts of new materials, super sticky glue, super strong lightweight materials, materials with memory and self-healing properties, are just on the horizon.